COMBINACION FARMACEUTICA PARA LA PREVENCION O TERAPIA DE ENFERMEDADES CARDIOVASCULARES, CARDIOPULMONARES, PULMONARES O RENALES

Uso del antagonista del receptor de la angiotensina II, telmisartan o de una de sus sales y del inhibidor de la reductasa de la HMG-CoA, simvastatina, para la preparación de un fármaco para el tratamiento de personas o mamíferos en los que está indicada la prevención o la terapia de enfermedades cardiovasculares, cardiopulmonares o renales. The use of the angiotensin II receptor antagonist telmisartan (I) (or its salt) and the 3-hydroxy-2-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor simvastatin (II) is claimed in the production of medicaments (A) for the treatment or prophylaxis of cardiovascular, cardiopulmonary or renal diseases. Independent claims are included for corresponding treatment methods and pharmaceutical compositions. ACTIVITY : Cardiant; Vasotropic; Hepatotropic; Hypotensive; Antilipemic; Antiarteriosclerotic; Antiasthmatic; Antiinflammatory; Antidiabetic; Cerebroprotective; Antianginal; Cytostatic; Antibacterial; Immunosuppressive; Vulnerary; Osteopathic; Neuroprotective; Nootropic. MECHANISM OF ACTION : Angiotensin II receptor antagonist; HMG-CoA reductase inhibitor; Peroxisome proliferator activated receptor-gamma (PPAR-gamma ) regulating gene expression inducer; Matrix metalloproteinase MMP-9 expression controller; Cytokine CD40L antagonist.