METODOS Y COMPOSICIONES PARA EL TRATAMIENTO

Método para determinar la intensidad del dolor percibido por un paciente que comprende: i. determinar la cantidad de marcador de dolor colinesterasa sérica en una muestra de líquidos biológicos obtenida del paciente durante un episodio doloroso; ii. comparar la cantidad de dicho marcador de dolor colinesterasa en dicha muestra con un patrón individualizado para un paciente, población de pacientes o grupo de individuos seleccionados; y iii.correlacionar la cantidad de dicha colinesterasa con un nivel objetivo de intensidad de dolor experimentado por el paciente en el momento de la toma de muestras. The present invention provides novel methods and diagnostic kits for the objective measurement of the severity of pain or stress being experienced by a patient with a disorder, diagnosis and treatment for patients suffering from painful disorders, and monitoring the effectiveness of different pain-treatment protocols. Pain-measuring methods comprise collecting a sample from a patient and determining the presence of a pain-associated marker in the sample. Methods for alleviating pain comprise administrating a dose of a therapeutically effective amount of a composition to the patient wherein the dose is determined by the presence of a pain-associated marker in a biological sample obtained from the patient. Compositions for alleviating pain comprise substances that are pain-associated markers or agents that interfere with pain-associated markers, and block or modulate the progression of pain perceived by the patient.