CTLA-8HUMANA Y USOS DE PROTEINAS RELACIONADAS CON CTLA-8

SE PRESENTAN POLINUCLEOTIDOS QUE CODIFICAN EL CTLA-8 HUMANO Y LAS PROTEINAS RELACIONADAS. SE PRESENTAN TAMBIEN LAS PROTEINAS HUMANAS CTLA-8 Y LOS METODOS PARA SU PRODUCCION. SE PRESENTAN TAMBIEN LOS METODOS DE TRATAMIENTO BASADOS EN LAS PROTEINAS HUMANAS CTLA-8 Y LAS PROTEINAS CTLA-8 DEL RATON Y LAS...

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Hauptverfasser:	PITTMAN, DEBRA, GOLDMAN, SAMUEL, CARLIN, MCKEOUGH, JACOBS, KENNETH, KELLEHER, KERRY, MI, SHA
Format:	Patent
Sprache:	spa
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Zusammenfassung:	SE PRESENTAN POLINUCLEOTIDOS QUE CODIFICAN EL CTLA-8 HUMANO Y LAS PROTEINAS RELACIONADAS. SE PRESENTAN TAMBIEN LAS PROTEINAS HUMANAS CTLA-8 Y LOS METODOS PARA SU PRODUCCION. SE PRESENTAN TAMBIEN LOS METODOS DE TRATAMIENTO BASADOS EN LAS PROTEINAS HUMANAS CTLA-8 Y LAS PROTEINAS CTLA-8 DEL RATON Y LAS PROTEINAS CTLA-8 DEL VIRUS DEL HERPES. An antibody that specifically reacts with a protein comprising an amino acid sequence selected from the group consisting of: (a) the amino acid sequence of SEQ ID NO:2; (b) the amino acid sequence of SEQ ID NO:2 from amino acids 11 to 163; (c) the amino acid sequence of SEQ ID NO:2 from amino acids 29 to 163; (d) the amino acid sequence of SEQ ID NO:2 from amino acids 31 to 163; and (e) a fragment of the amino acid sequence of SEQ ID NO:2 having a CTLA-8 activity chosen from one or more of induction of expression or secretion of gamma -IFN, IL-6, or IL-8, or inhibition of angiogenesis.