COMPOSICIONES ANTIPARASITARIAS

LA INVENCION CONCIERNE EL ENVIO DE AGENTES ANTIPARASITARIOS A ANIMALES RUMIANTES. MAS PARTICULARMENTE, LA INVENCION CONCIERNE EL ENVIO DE TALES AGENTES DE MANERA CONTROLADA PARA PERMITIR QUE EL AGENTE TENGA UN EFECTO MAXIMO SOBRE EL PARASITO DURANTE PERIODOS DE TIEMPO MAS LARGOS, QUE LO QUE ES POSIBLE CON FORMULACIONES CONVENCIONALES. LA COMPOSICION DE LA INVENCION INCLUYE UNA BENZINIDAZOLA, LACTONA MACROCICLICA, ORGANO FOSFATO, UN FENOL SALICILANILIDO/SUSTITUIDO, O UN AGENTE DE TETRAMISOLA O PIRIMIDINA ANTIPARASITARIO DISPERSADO EN UN MEDIO CUYAS CARACTERISTI CAS DE SOLUBILIDAD SON TALES QUE ASEGURAN QUE, SIGUIENDO SU ADMINISTRACION ORAL, CANTIDADES CONTROLADAS DEL AGENTE ANTIPARASITARIO SE HAGAN DISPONIBLES AL PARASITO, BIEN DIRECTAMENTE O POR UNA ABSORCION EN EL PLASMA SANGUINEO DEL RUMIANTE, DURANTE EL PASO DE LA COMPOSICION A TRAVES DEL RUMEN, EL ABOMASO Y EL INTESTINO. PCT No. PCT/AU94/00272 Sec. 371 Date Mar. 13, 1996 Sec. 102(e) Date Mar. 13, 1996 PCT Filed May 24, 1994 PCT Pub. No. WO94/27598 PCT Pub. Date Dec. 8, 1994This invention concerns the delivery of anti-parasitic agents to ruminant animals. More particularly, the invention concerns delivery of such agents in a controlled manner to enable the agent to have maximum effect on the parasite for longer times than is possible with conventional formulations. The composition of the invention comprises a benzimidazole, macrocyclic lactone, organophosphate, salicylanilide/substituted phenol, tetramisole or pyrimidine anti-parasitic agent dispersed in a medium the solubility characteristics of which are such as to ensure that, following oral administration, controlled amounts of the anti-parasitic agent become available to the parasite, either directly or by absorption into the ruminant blood plasma, during passage of the composition through the rumen, the abomasum and the intestine.