ANTIBIOTICOS DE CEFALOSPORINA

LA PRESENTE INVENCION TRATA DE NUEVOS ACIDOS (7R) - 7 (ACILAMINO) - 3 - (ARILTIO) - 3 - CEFEM - 4 - CARBOXILICOS O SUS SALES FARMACEUTICAMENTE ACEPTABLES QUE TIENEN ACTIVIDAD ANTIBIOTICA CONTRA UN AMPLIO ESPECTRO DE ORGANISMOS INCLUYENDO ORGANISMOS QUE SON RESISTENTES A LOS ANTIBIOTICOS DE BE LACTAMAS Y SON UTILES COMO AGENTES ANTIBACTERIANOS. LA INVENCION TAMBIEN TRATA DE NUEVOS COMPUESTOS INTERMEDIOS UTILES PARA SINTETIZAR LOS NUEVOS COMPUESTOS DE LA PRESENTE INVENCION Y DE NUEVOS PROCEDIMIENTOS PARA OBTENER LOS NUEVOS COMPUESTOS Y COMPUESTOS INTERMEDIOS. The present invention includes novel compounds of formula where R99 is selected from the group consisting of sulfur, SO, SO2, NH, N-alkyl, oxygen, C=C (cis or trans), and C 3BOND C, and R12 is The invention also includes the pharmacologically acceptable salts which exhibit antibiotic activity against a wide spectrum of organisms including organisms which are resistant to beta -lactam antibiotics and are useful as antibacterial agents. The invention also relates to novel intermediates useful for making the novel compounds of the present invention and to novel methods for producing the novel compounds and intermediate compounds.