ANDROSTENONAS

LA INVENCION SE REFIERE A COMPUESTOS DE LA FORMULA (I), EN DONDE LOS CARBONOS 1 Y 2 ESTAN UNIDOS BIEN POR UN ENLACE SIMPLE O BIEN POR UN ENLACE DOBLE; R1 ES HIDROGENO O METILO; R2 ES HIDROGENO O METILO; R3 ES (A) O (B) EN DONDE X, W, Z, R4, R5, R6, R7 Y R8 SON DIFERENTES GRUPOS, TAMBIEN SE PRESENTAN LOS SOLVATOS FARMACOLOGICAMENTE ACEPTABLES DE LOS MISMOS Y SU USO EN EL TRATAMIENTO DE ENFERMEDADES INTERMEDIADAS Y SENSIBLES A LOS ANDROGENOS. A compound of formula (I) wherein carbons 1 and 2 are joined by either a single or a double bond; R is hydrogen or methyl; R is hydrogen or methyl; R is (A) wherein R and R are independently hydrogen, straight or branched alkyl of 1 to 6 carbon atoms, straight or branched alkoxy of 1 to 6 carbon atoms, trifluoromethyl, cyano, halogen, phenyl (optionally substituted with one or more halogens), or when R and R are on adjacent carbons, taken together form a fused 5, 6 or 7 member ring optionally containing one or more oxygen or sulfur atoms; W and Z are methylene groups which taken together with the carbon to which they are attached form a saturated, 3 to 12 member ring system optionally: 1) substituted independently with one or more lower alkyl groups, 2) containing an oxygen or sulfur atom, 3) two said methylene groups of said 3 to 12 member ring are joined with a (C1-6) alkylene group to form a bicyclic ring system; and X is hydrogen or halogen; or a pharmaceutically acceptable solvate thereof.