Protein Euserratin 1 from the plant Euphorbia serrata L., process for obtaining it and its use

Protein Euserratin 1 from the plant Euphorbia serrata L., process for obtaining it and its use. Euserratin 1 has the following amino acid composition Cys- 0.8, Asp-32.6, Thr-22.2, Ser-17.4, Glu-24.2, Pro-10.8, Gly-13.1, Ala-15.2, Val-24.7, Met-3.4, Ile-17.8, Leu- 38.7, Tyr-8.7, Phe-11.6, Lys-20.5, His-5.4, Arg-9.2. The process comprises (a) extracting a lyophilisate of Euphorbia serrata L., (b) filtering the liquid extract through a chromatographic bed, (c) subjecting the extracted fluid to ion exchange chromatography, (d) eluting the column with a solution of NaCl and NaH2PO4, (e) dialysing the eluted protein and subjecting it to ion exchange chromatography, (f) purifying the Euserratin 1 by molecular exclusion and ion exchange chromatography. Euserratin 1 is used as a ribonucleic acid inactivator and an inhibitor of protein synthesis. PROTEINA EUSERRATINA 1 DE LA PLANTA EUPHORBIA SERRATA L., PROCEDIMIENTO PARA SU OBTENCION Y SU UTILIZACION. LA EUSERRATINA 4 PRESENTA LA SIGUIENTE COMPOSICION DE AMINOACIDOS: CYS-0,8, ASP-32,6, THR-22,2, SER-17,4, GLU-24,2, PRO-10,8, GLY-13,1, ALA-15,2, VAL-24,7, MET-3,4, ILE-17,8, LEU-38,7, TYR-8,7, PHE-11,6, LYS-20,5, HIS-5,4, ARG-9,2. EL PROCEDIMIENTO COMPRENDE: (A) EXTRAER UN LIOFILIZADO DE EUPHORBIA SERRATA L.; (B) FILTRAR EL EXTRACTO LIQUIDO POR UN LECHO CROMATOGRAFICO; (C) SOMETER EL FLUIDO EXTRAIDO A CROMATOGRAFIA DE INTERCAMBIO IONICO; (D) ELUIR LA COLUMNA CON UNA SOLUCION DE CLNA Y NAPO4H2; (E) DIALIZAR LA PROTEINA ELUIDA Y SOMETERLA A CROMATOGRAFIA DE INTERCAMBIO IONICO; (F) PURIFICAR LA EUSERRATINA 1, POR CROMATOGRAFIA DE EXCLUSION MOLECULAR Y DE INTERCAMBIO IONICO. LA EUSERRATINA 1 SE UTILIZA COMO INACTIVADOR DEL ACIDO RIBONUCLEICO E INHIBIDOR DE LA SINTESIS DE PROTEINAS.