CONJUGADOS PROTEICOS MAGNETICOS, PROCEDIMIENTO PARA SU PREPARACION Y SU EMPLEO

CONJUGADOS DE PROTEINA MAGNETICOS CON FORMULA (I) (FORMULA) EN LA QUE N = 1 A 6, CON PREFERENCIA N = 1 O 2, SIENDO M MATERIALES O PARTICULAS DISPERSABLES, QUE REACCIONA MAGNETICAMENTE, CON GRUPOS AMINO Y P UNA PROTEINA. PROCEDIMIENTO DE FABRICACION Y APLICACIONES PARA LA ELIMINACION DE CELULAS O ANT...

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Hauptverfasser:	DONGES, REINER, FRIESEN, HEINZ-JURGEN, FRANSSEN, UDO, HERMENTIN, PETER, ENSSLE, KARLHEINZ
Format:	Patent
Sprache:	spa
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING VINEGAR WINE
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Zusammenfassung:	CONJUGADOS DE PROTEINA MAGNETICOS CON FORMULA (I) (FORMULA) EN LA QUE N = 1 A 6, CON PREFERENCIA N = 1 O 2, SIENDO M MATERIALES O PARTICULAS DISPERSABLES, QUE REACCIONA MAGNETICAMENTE, CON GRUPOS AMINO Y P UNA PROTEINA. PROCEDIMIENTO DE FABRICACION Y APLICACIONES PARA LA ELIMINACION DE CELULAS O ANTIGENES, RECEPTORES, SUBSTRATOS, ETC DE SOLUCIONMES ACUOSAS SALINAS. The invention relates to magnetic protein conjugates of the formula I M-NH-CO-(CH2)n-S-P'I with n=1-6, preferably with a n=1 or 2 and particularly preferably with n=1, in which M is a dispersible, magnetically reacting material or particle which carries amino groups, and P' is a protein, to a process for the preparation thereof and to the use thereof for the specific removal of cells or soluble antigens, receptors, substrates, cofactors or carbohydrate determinants from aqueous salt solutions or body fluids or as part of a diagnostic method or as a diagnostic aid, preferably for the removal of cells, preferably for bone marrow depletion or for HLA typing.