Method of purifying factor VIII:C

Method of purifying factor VIII:C

Disclosed is a process for purifying Factor VIII:C in high yield and potency from source material containing Factor VIII:C, Factor VIII:R and other plasma proteins and factors comprising the steps of: adsorbing Factor VIII:C onto a hydrophobic interaction matrix, separating unwanted proteins from Fa...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: FARB DAVID L, LANDABURU RICARDO H
Format: Patent
Sprache:eng ; spa
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Disclosed is a process for purifying Factor VIII:C in high yield and potency from source material containing Factor VIII:C, Factor VIII:R and other plasma proteins and factors comprising the steps of: adsorbing Factor VIII:C onto a hydrophobic interaction matrix, separating unwanted proteins from Factor VIII:C and eluting Factor VIII:C by a solution containing a surface active agent. SE REVELA UN METODO PARA PURIFICAR FACTOR VIII:C CON ALTO RENDIMIENTO Y POTENCIA A PARTIR DE MATERIAL DE FUENTE QUE CONTIENE FACTOR VIII:C,FACTOR VIII:R Y OTRAS PROTEINAS Y FACTORES DEL PLASMA, EL CUAL PROCEDIMIENTO COMPRENDE LAS ETAPAS DE: ABSORBER FACTOR VIII:C EN UNA MATRIZ DE INTERACCION HIDROFOBA, SEPARAR LAS PROTEINAS NO DESEADAS DEL FACTOR VIII:C Y ELUDIR FACTOR VIII:C POR MEDIO DE UNA DISOLUCION.