METHODS OF PROCESSING A FLUID

Provided herein are methods of processing a fluid comprising a recombinant therapeutic protein that include the use of a bioprocessing system comprising integrated unit operations, including cell removal, cell retention, chromatography, virus inactivation, virus filtration, TFF, and formulation. Als...

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Bibliographische Detailangaben
Hauptverfasser: MALLADI, Shashi, COOLBAUGH, Michael
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:Provided herein are methods of processing a fluid comprising a recombinant therapeutic protein that include the use of a bioprocessing system comprising integrated unit operations, including cell removal, cell retention, chromatography, virus inactivation, virus filtration, TFF, and formulation. Also provided are bioprocessing systems that include these unit operations.