PYRROLOBENZODIAZEPINE INTERMEDIATES AND USES THEREOF

Pyrrolobenzodiazepine (PBD) intermediates, including useful in the preparation of advanced intermediates, PBDs, and PBD dimers. Such PBD intermediates provide several advantages, including simplified synthesis of desired PBD products, greater substrate compatibility, and safer reaction conditions.

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Bibliographische Detailangaben
Hauptverfasser: GROSO, Emilia, WALKER, James, WRIGHT, Austin, BEMOWSKI, Ross, BERG, Logan, P T, Sheshagiri, REDFERN, Louis, AIWALE, Sachin Tanaji, GOEDDEL, David, SINGH, Ravindra Vikram
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Pyrrolobenzodiazepine (PBD) intermediates, including useful in the preparation of advanced intermediates, PBDs, and PBD dimers. Such PBD intermediates provide several advantages, including simplified synthesis of desired PBD products, greater substrate compatibility, and safer reaction conditions.