OIL-IN-WATER EMULSION WITH AGAR AND DIACETYL TARTARIC ACID ESTERS OF MONO-AND DI-GLYCERIDES (DATEM)

The invention relates to compositions for oral administration which are provided in the form of gelled oil-in-water emulsions, to methods for their preparation and to their use as pharmaceuticals and nutraceuticals. In particular, it relates to orally administrable, gelled oil-in-water emulsions whi...

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Hauptverfasser: DRAGET, Kurt Ingar, DILLE, Morten J, HATTREM, Magnus N
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The invention relates to compositions for oral administration which are provided in the form of gelled oil-in-water emulsions, to methods for their preparation and to their use as pharmaceuticals and nutraceuticals. In particular, it relates to orally administrable, gelled oil-in-water emulsions which are self-supporting, viscoelastic solids having a gelled aqueous phase comprising a gelling agent which is agar, wherein said emulsion has a water activity in the range of about 0.4 to about 0.9 and is stabilised by a surfactant which comprises an ester of glycerol in which at least one hydroxyl group is esterified by diacetyl tartaric acid and at least one hydroxyl group is esterified by a fatty acid.