MEDICINAL SALT OF CARIPRAZINE AND CRYSTAL FORM THEREOF, PHARMACEUTICAL COMPOSITION THEREOF, AND PREPARATION METHOD THEREFOR AND USE THEREOF

Disclosed are 1-hydroxy-2-naphthoate or bis-hydroxynaphthenate of cariprazine, a new solid form thereof, a pharmaceutical composition thereof, and a preparation method therefor and the use thereof. The cariprazine salt and the solid form thereof, especially 1-hydroxy-2-naphthoate of cariprazine in an insoluble salt of cariprazine has the advantages of a long-acting sustained-release preparation, can be developed into a suspension injection, can also solve the problems of the risk of the dissociation or the lack of sustained release effect of existing salt types such as cariprazine hydrochloride, can achieve the effect of long-acting administration, and greatly improves the compliance of a patient and the bioavailability and medication safety of a drug.