RADIOACTIVE COMPLEX OF ANTI-VEGF ANTIBODY, AND RADIOPHARMACEUTICAL

the present invention aims to provide a novel radiolabeled anti-VEGF antibody applicable to nuclear medicine diagnosis or radiotherapy. The conjugate of the present invention is a conjugate of an antibody which is site-specifically modified with an antibody-modification peptide and a chelating agent...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	NARITA, Yudai, ABE, Yuju, KISHIMOTO, Satoshi, TAKENAKA, Fumiaki, OTSUKA, Yuta, HANADA, Takahisa
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	the present invention aims to provide a novel radiolabeled anti-VEGF antibody applicable to nuclear medicine diagnosis or radiotherapy. The conjugate of the present invention is a conjugate of an antibody which is site-specifically modified with an antibody-modification peptide and a chelating agent, wherein the antibody is an anti-VEGF antibody and a metal radionuclide is chelated to the chelating agent.