ANTI-ASGR1 POLYPEPTIDES AND METHODS OF USE FOR IMMUNE TOLERANCE

Disclosed herein are binding polypeptides that bind to asialoglycoprotein receptor 1 (ASGR1), and methods of use thereof for inducing immune tolerance against antigens of interest, for example, for treating, ameliorating, inhibiting, or preventing disease or disorders associated with unwanted immune...

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Hauptverfasser: GOLDSTEIN, Rebecca Ilene, PAULI, Noel Thomas, CONLEY, Gregory Paul, WASSAF, Dina Sami, SILVERMAN, Julie Michelle, KONTOS, Stephan, NIELSON, Nels Peter, II
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Disclosed herein are binding polypeptides that bind to asialoglycoprotein receptor 1 (ASGR1), and methods of use thereof for inducing immune tolerance against antigens of interest, for example, for treating, ameliorating, inhibiting, or preventing disease or disorders associated with unwanted immune response against the antigens of interest, such as autoimmune diseases.