SENSOR MEASUREMENT COMPENSATION IN BIOPROCESSING SYSTEMS

A pH system that is able to compensate for variations in pressure and conductivity is disclosed. The system includes a pH sensor, a pressure sensor and optionally a conductivity sensor, the outputs of each are transmitted to a controller. The controller multiplies a compensation coefficient by the d...

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Bibliographische Detailangaben
Hauptverfasser:	DA SILVA, Anthony, SPINDLER, Quentin, COTON, Thomas, JOURDAINNE, Laurent
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	A pH system that is able to compensate for variations in pressure and conductivity is disclosed. The system includes a pH sensor, a pressure sensor and optionally a conductivity sensor, the outputs of each are transmitted to a controller. The controller multiplies a compensation coefficient by the difference in pressure between the measured pressure and a threshold pressure. This result is then added to the measured pH value. Further, the compensation coefficient is a function of the conductivity of the solution. In some instances, the compensation coefficient is calculated by raising the conductivity to a power and multiplying that result by a constant. This pH system may be incorporated into various bioprocessing systems, such as multi- column chromatography systems and viral inactivation systems.