COMBINATION THERAPY WITH ARENAVIRUS PARTICLES AND IMMUNE CHECKPOINT MODULATORS OR CYTOKINES

COMBINATION THERAPY WITH ARENAVIRUS PARTICLES AND IMMUNE CHECKPOINT MODULATORS OR CYTOKINES

Provided herein are methods and compositions for the treatment of neoplastic and infectious diseases. Specifically, provided herein are combination treatments that combine arenavirus-vectored antigens, such as tumor antigens or antigens of pathogens, with various immune checkpoint modulators or cyto...

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Bibliographische Detailangaben
Hauptverfasser: RAGUZ, Josipa, SCHMIDT, Sarah, LAUTERBACH, Henning, SCHIPPERS, Timo, STRAUSS, Judith, AHMADI-ERBER, Sarah, ORLINGER, Klaus
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Provided herein are methods and compositions for the treatment of neoplastic and infectious diseases. Specifically, provided herein are combination treatments that combine arenavirus-vectored antigens, such as tumor antigens or antigens of pathogens, with various immune checkpoint modulators or cytokines, which may in turn themselves be expressed using the arenavirus-based expression system.