3-[(BENZO[D][1,3]DIOXOLANE-4-YL)OXY]PROPYLAMINE HYDROCHLORIDE, OPTICAL ISOMER AND CRYSTAL THEREOF, AND PREPARATION METHOD THEREFOR

3-[(BENZO[D][1,3]DIOXOLANE-4-YL)OXY]PROPYLAMINE HYDROCHLORIDE, OPTICAL ISOMER AND CRYSTAL THEREOF, AND PREPARATION METHOD THEREFOR

The present application relates to a 3-[(benzo[d][1,3]dioxolane-4-yl)oxy]propylamine hydrochloride, a crystalline form thereof, and a preparation method therefor. A crystal form A of an (R)-N-methyl-3-phenyl-3-[(benzo[d][1,3]dioxolane-4-yl)oxy]propylamine hydrochloride prepared in the present invent...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: DUAN, Chen, XU, Xiangqing, LI, Quxiang, SONG, Yadong, GUO, Qiang
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The present application relates to a 3-[(benzo[d][1,3]dioxolane-4-yl)oxy]propylamine hydrochloride, a crystalline form thereof, and a preparation method therefor. A crystal form A of an (R)-N-methyl-3-phenyl-3-[(benzo[d][1,3]dioxolane-4-yl)oxy]propylamine hydrochloride prepared in the present invention has good crystal form stability and chemical stability, and can be better used for clinical treatment.