AN INTRAVAGINAL RING

The present invention relates to an intravaginal ring (1) a core (2) comprising a first ethylene-vinyl acetate copolymer (3) having a vinyl acetate content from 28 to 40%, and at least 10 wt% of an estrogenic steroid (4) based on the weight of the core, and a sheath (5) comprising a second ethylene-...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: VAN LAARHOVEN, Hans, DE GRAAFF, Wouter
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The present invention relates to an intravaginal ring (1) a core (2) comprising a first ethylene-vinyl acetate copolymer (3) having a vinyl acetate content from 28 to 40%, and at least 10 wt% of an estrogenic steroid (4) based on the weight of the core, and a sheath (5) comprising a second ethylene-vinyl acetate copolymer (6) having a vinyl acetate content from 18 to 28%, and at least 10 wt% of a progestational steroid (7) based on the weight of the sheath. Using the intravaginal ring according to the present the inventors have found that it is possible to attain independent and optimal release of the two active ingredients; an estrogenic steroid and a progestational steroid, without the need for complex assembly of parts and without the need to use sophisticated multi-layer extrusion technology.