ANTIBODY SPECIFIC TO NECTIN CELL ADHESION MOLECULE 4 AND USES THEREOF

The present disclosure relates to a modified antibody, or antigen-binding fragment thereof, specific for nectin cell adhesion molecule 4 (nectin-4). The present disclosure also relates to a method of detecting or diagnosing whether a subject has, or is at risk of developing a tumor, or assessing a p...

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Bibliographische Detailangaben
Hauptverfasser:	TSAI, Bor-Yu, HUANG, Shin-Tsung, HSU, Wei-Ting
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present disclosure relates to a modified antibody, or antigen-binding fragment thereof, specific for nectin cell adhesion molecule 4 (nectin-4). The present disclosure also relates to a method of detecting or diagnosing whether a subject has, or is at risk of developing a tumor, or assessing a prognosis of a tumor and a pharmaceutical composition for use in treating, prophylactic treating and/or preventing tumor in a subject afflicted with the tumor.