NOVEL ARTIFICIAL NUCLEIC ACID, METHOD FOR PRODUCING SAME, AND USE OF SAME
The present invention provides an artificial nucleic acid having units derived from compound represented by formula (1) or a salt thereof(wherein "Base" represents an aromatic heterocyclic group which may have a substituent, or an aromatic hydrocarbon ring group which may have a substituen...
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Format: | Patent |
Sprache: | eng ; fre ; ger |
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Zusammenfassung: | The present invention provides an artificial nucleic acid having units derived from compound represented by formula (1) or a salt thereof(wherein "Base" represents an aromatic heterocyclic group which may have a substituent, or an aromatic hydrocarbon ring group which may have a substituent;X1 represents a hydrogen atom, an alkyl group which may have a substituent, an alkenyl group which may have a substituent, an alkynyl group which may have a substituent, a cycloalkyl group which may have a substituent, or an aryl group which may have a substituent; X2 represents a hydrogen atom or -OR7; R1, R2, and R7 are the same as or different from each other and independently represent a hydrogen atom, an alkyl group which may have a substituent, an alkenyl group which may have a substituent, an alkynyl group which may have a substituent, a cycloalkyl group which may have a substituent, a cycloalkenyl group which may have a substituent, an aryl group which may have a substituent, a protecting group for a hydroxy group, a phosphino group which has a substituent, a dihydroxyphosphinyl group which may have a substituent, or a hydroxymercaptophosphinyl group which may have a substituent; R3, R4, R5, and R6 are the same as or different from each other and independently represent a hydrogen atom, an alkyl group which may have a substituent, an alkenyl group which may have a substituent, an alkynyl group which may have a substituent, a cycloalkyl group which may have a substituent, or an aryl group which may have a substituent; Z1 represents O or NZ11; Z11 represents a hydrogen atom, an alkyl group, an alkenyl group, an alkynyl group, a cycloalkyl group, an aryl group, an aralkyl group, or a protecting group for an amino group; Z2 represents a single bond or CZ21Z22; and Z21 and Z22 are the same as or different from each other and independently represent a hydrogen atom, an alkyl group which may have a substituent, an alkenyl group which may have a substituent, an alkynyl group which may have a substituent, a cycloalkyl group which may have a substituent, or an aryl group which may have a substituent). |
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