METHODS AND SYSTEMS FOR TRANSFECTING HOST CELLS

The present disclosure pertains to methods for transducing host cells with nucleic acids using an in-line complexer and systems comprising an in-line complexer for transducing host cells. The disclosed methods and systems can be used to produce recombinant adeno-associated virus (rAAV) particles. Al...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: VACA, Alexander, SHUPE, Jenny Wang-Yuanzhen
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The present disclosure pertains to methods for transducing host cells with nucleic acids using an in-line complexer and systems comprising an in-line complexer for transducing host cells. The disclosed methods and systems can be used to produce recombinant adeno-associated virus (rAAV) particles. Also disclosed herein are compositions comprising rAAV particles obtained from the disclosed methods and systems, and uses of the same.