PHOTOCHEMICAL APPROACH TO C-TERMINAL A-AMIDATION

PHOTOCHEMICAL APPROACH TO C-TERMINAL A-AMIDATION

The present invention relates to a photochemical process for the manufacturing of a C-terminal α-amide, which are a class of compounds that represent up to half of all biologically relevant peptide hormones. The invention provides mild, broad in scope, economically efficient process, which is suitab...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: WONG, Sydnee, WOJCIK, Felix, WILLIAMS, Benjamin, Matthew, HOGENDORF, Wouter, Frederik, Johan, HYMEL, David, Thomas, COX, Nicholas, Raymond, MORTENSEN, Asmus, Ringlebjerg, HARRIS, Michael, Richard
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Beschreibung
Zusammenfassung:The present invention relates to a photochemical process for the manufacturing of a C-terminal α-amide, which are a class of compounds that represent up to half of all biologically relevant peptide hormones. The invention provides mild, broad in scope, economically efficient process, which is suitable for large scale manufacturing.