TAURINE SUPPLEMENTED CELL CULTURE MEDIUM AND METHODS OF USE

The specification describes a composition comprising an improved eukaryotic cell culture medium, which can be used for the production of a protein of interest. Taurine can be added to serum-free media or chemically-defined media to increase the production of a protein of interest. Methods for recomb...

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Bibliographische Detailangaben
Hauptverfasser: OSHODI, Shadia, JOHNSON, Amy S, LAWRENCE, Shawn, CASEY, Meghan E
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The specification describes a composition comprising an improved eukaryotic cell culture medium, which can be used for the production of a protein of interest. Taurine can be added to serum-free media or chemically-defined media to increase the production of a protein of interest. Methods for recombinantly expressing high levels of protein using the media compositions are included.