CCR8 ANTIGEN BINDING UNIT AND USES THEREOF

Described here is are antibodies to CCR8 having enhanced binding, ligand blocking and antibody dependent cellular cytotoxicity. Also described is are methods of treating a cancer by targeting tumor infiltrating lymphocytes in a cancer patient using a formulation comprising a CCR8 antibody described...

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Bibliographische Detailangaben
Hauptverfasser:	KANG, Lishan, CHEN, Min, DAI, Xinchuan, BELLOVIN, David, WANG, Lina, LIU, Hongshui, WAN, Bing, SHI, Wenhua, YIN, Shang, ZHANG, Jing, LI, Shou
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Described here is are antibodies to CCR8 having enhanced binding, ligand blocking and antibody dependent cellular cytotoxicity. Also described is are methods of treating a cancer by targeting tumor infiltrating lymphocytes in a cancer patient using a formulation comprising a CCR8 antibody described above.