FRAGMENT CONSENSUS METHODS FOR ULTRASENSITIVE DETECTION OF ABERRANT METHYLATION

Provided herein are methods related to detecting DNA methylation (e.g., level of methylation at CpG dinucleotide cluster(s)), as well as methods of treatment, uses, systems, and computer readable storage media related thereto. These methods allow for detection of aberrant DNA methylation patterns wi...

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Hauptverfasser: PETERMAN, Neil, ROBERTSON, Alexander De Jong, LAMBERT, Nicole Jacinda
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creator PETERMAN, Neil
ROBERTSON, Alexander De Jong
LAMBERT, Nicole Jacinda
description Provided herein are methods related to detecting DNA methylation (e.g., level of methylation at CpG dinucleotide cluster(s)), as well as methods of treatment, uses, systems, and computer readable storage media related thereto. These methods allow for detection of aberrant DNA methylation patterns with low background and increased signal-to-background ratio, which can be useful, inter alia, in the early detection or monitoring of cancer.
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language eng ; fre ; ger
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
ENZYMOLOGY
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
PROCESSES OF PREPARING SUCH COMPOSITIONS
SPIRITS
VINEGAR
WINE
title FRAGMENT CONSENSUS METHODS FOR ULTRASENSITIVE DETECTION OF ABERRANT METHYLATION
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