COMPOSITIONS AND METHODS OF RIBONUCLEIC ACID RESPIRATORY SYNCYTIAL VIRUS (RSV) VACCINES

Provided herein is a ribonucleic acid (RNA) encoding a fusion glycoprotein (F) protein or an immunogenic fragment thereof of a respiratory syncytial virus (RSV) comprising at least one non-naturally occurring amino acid mutation. Additionally provided are relevant polynucleotides, vectors, cells, co...

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Bibliographische Detailangaben
Hauptverfasser: BROWN, David, CHEN, Renxiang, ANANTHASWAMY, Neeti
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Provided herein is a ribonucleic acid (RNA) encoding a fusion glycoprotein (F) protein or an immunogenic fragment thereof of a respiratory syncytial virus (RSV) comprising at least one non-naturally occurring amino acid mutation. Additionally provided are relevant polynucleotides, vectors, cells, compositions, kits, production methods and methods of use.