TRANS-CYCLOOCTENE WITH IMPROVED T-LINKER

TRANS-CYCLOOCTENE WITH IMPROVED T-LINKER

Disclosed herein are trans-cyclooctenes (TCOs) that have an improved T-linker. In particular, the TCOs have improved in vitro and in vivo properties as compared to TCOs known from the prior art. The disclosure also pertains to in vivo and in vitro methods of using said trans-cyclooctenes, as well as...

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Bibliographische Detailangaben
Hauptverfasser: ROSSIN, Raffaella, KLEIJN, Laurens Henri Johan, ROBILLARD, Marc Stefan
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Disclosed herein are trans-cyclooctenes (TCOs) that have an improved T-linker. In particular, the TCOs have improved in vitro and in vivo properties as compared to TCOs known from the prior art. The disclosure also pertains to in vivo and in vitro methods of using said trans-cyclooctenes, as well as medical uses thereof.