ANTIBODY OR FRAGMENT THEREOF BINDING SPECIFICALLY TO MERTK, AND ANTI-TUMOR AGENT

A problem addressed by the present invention is to provide an anti-MerTK antibody that has a tumor-suppressing effect and does not tend to cause ocular toxicity. The present invention provides an antibody or a fragment thereof that binds specifically to MerTK, in which the amino acid sequences of he...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	SAWADA, Atsushi, TAKESUE, Aki, TOYOURA, Masayoshi, KAMBAYASHI, Hiroaki, INOUE, Toshikazu
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	A problem addressed by the present invention is to provide an anti-MerTK antibody that has a tumor-suppressing effect and does not tend to cause ocular toxicity. The present invention provides an antibody or a fragment thereof that binds specifically to MerTK, in which the amino acid sequences of heavy chain and light chain CDRs 1 to 3 satisfy predetermined requirements.