SOLUTION PHASE POLYMER SYNTHESIS

SOLUTION PHASE POLYMER SYNTHESIS

A membrane-assisted process for the preparation of defined monomer sequence polymers, including oligonucleotides and peptides, in solution phase is described. The growing defined monomer sequence polymer is attached to a soluble synthesis support having properties that allow the polymer to be straig...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: LIVINGSTON, Andrew Guy, GAFFNEY, Piers Robert James
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
DERIVATIVES THEREOF
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
SEPARATION
SUGARS
TRANSPORTING
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Beschreibung
Zusammenfassung:A membrane-assisted process for the preparation of defined monomer sequence polymers, including oligonucleotides and peptides, in solution phase is described. The growing defined monomer sequence polymer is attached to a soluble synthesis support having properties that allow the polymer to be straightforwardly prepared in certain industry-favoured solvents with improved membrane flux and reduced fouling.