MULTISPECIFIC BINDING AGENTS AGAINST PD-L1 AND CD137 IN COMBINATION
The present invention provides combination therapy using a binding agent that binds to human CD137 and to human PD-L1 in combination with a PD-1 inhibitor to reduce or prevent progression of a tumor or treating cancer.
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; fre ; ger |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | KUZMANOV, Ivan PENCHEVA, Nora BLUM, Jordan FELLERMEIER-KOPF, Sina SAHIN, Ugur PAULMANN, Claudia BREIJ, Esther C. W BECKMANN, Karsten MUIK, Alexander LABRIJN, Aran HIBBERT, Richard GARRIDO CASTRO, Patricia DE KREUK, Bart-Jan GIESEKE, Friedericke GUELEN, Lars NÜRMBERGER, Kristina JURE-KUNKEL, Maria,N NEIJSSEN, Joost SCHUURMAN, Janine |
| description | The present invention provides combination therapy using a binding agent that binds to human CD137 and to human PD-L1 in combination with a PD-1 inhibitor to reduce or prevent progression of a tumor or treating cancer. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_EP4413040A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>EP4413040A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_EP4413040A13</originalsourceid><addsrcrecordid>eNrjZHD2DfUJ8QwOcHX2dPN0VnDy9HPx9HNXcHR39QsJBlKOnn7BIQoBLro-hgqOfi4Kzi6GxuYKnn4Kzv6-QMWOIZ7-fjwMrGmJOcWpvFCam0HBzTXE2UM3tSA_PrW4IDE5NS-1JN41wMTE0NjAxMDR0JgIJQCKrypE</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>MULTISPECIFIC BINDING AGENTS AGAINST PD-L1 AND CD137 IN COMBINATION</title><source>esp@cenet</source><creator>KUZMANOV, Ivan ; PENCHEVA, Nora ; BLUM, Jordan ; FELLERMEIER-KOPF, Sina ; SAHIN, Ugur ; PAULMANN, Claudia ; BREIJ, Esther C. W ; BECKMANN, Karsten ; MUIK, Alexander ; LABRIJN, Aran ; HIBBERT, Richard ; GARRIDO CASTRO, Patricia ; DE KREUK, Bart-Jan ; GIESEKE, Friedericke ; GUELEN, Lars ; NÜRMBERGER, Kristina ; JURE-KUNKEL, Maria,N ; NEIJSSEN, Joost ; SCHUURMAN, Janine</creator><creatorcontrib>KUZMANOV, Ivan ; PENCHEVA, Nora ; BLUM, Jordan ; FELLERMEIER-KOPF, Sina ; SAHIN, Ugur ; PAULMANN, Claudia ; BREIJ, Esther C. W ; BECKMANN, Karsten ; MUIK, Alexander ; LABRIJN, Aran ; HIBBERT, Richard ; GARRIDO CASTRO, Patricia ; DE KREUK, Bart-Jan ; GIESEKE, Friedericke ; GUELEN, Lars ; NÜRMBERGER, Kristina ; JURE-KUNKEL, Maria,N ; NEIJSSEN, Joost ; SCHUURMAN, Janine</creatorcontrib><description>The present invention provides combination therapy using a binding agent that binds to human CD137 and to human PD-L1 in combination with a PD-1 inhibitor to reduce or prevent progression of a tumor or treating cancer.</description><language>eng ; fre ; ger</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240814&DB=EPODOC&CC=EP&NR=4413040A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,309,781,886,25569,76552</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240814&DB=EPODOC&CC=EP&NR=4413040A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KUZMANOV, Ivan</creatorcontrib><creatorcontrib>PENCHEVA, Nora</creatorcontrib><creatorcontrib>BLUM, Jordan</creatorcontrib><creatorcontrib>FELLERMEIER-KOPF, Sina</creatorcontrib><creatorcontrib>SAHIN, Ugur</creatorcontrib><creatorcontrib>PAULMANN, Claudia</creatorcontrib><creatorcontrib>BREIJ, Esther C. W</creatorcontrib><creatorcontrib>BECKMANN, Karsten</creatorcontrib><creatorcontrib>MUIK, Alexander</creatorcontrib><creatorcontrib>LABRIJN, Aran</creatorcontrib><creatorcontrib>HIBBERT, Richard</creatorcontrib><creatorcontrib>GARRIDO CASTRO, Patricia</creatorcontrib><creatorcontrib>DE KREUK, Bart-Jan</creatorcontrib><creatorcontrib>GIESEKE, Friedericke</creatorcontrib><creatorcontrib>GUELEN, Lars</creatorcontrib><creatorcontrib>NÜRMBERGER, Kristina</creatorcontrib><creatorcontrib>JURE-KUNKEL, Maria,N</creatorcontrib><creatorcontrib>NEIJSSEN, Joost</creatorcontrib><creatorcontrib>SCHUURMAN, Janine</creatorcontrib><title>MULTISPECIFIC BINDING AGENTS AGAINST PD-L1 AND CD137 IN COMBINATION</title><description>The present invention provides combination therapy using a binding agent that binds to human CD137 and to human PD-L1 in combination with a PD-1 inhibitor to reduce or prevent progression of a tumor or treating cancer.</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZHD2DfUJ8QwOcHX2dPN0VnDy9HPx9HNXcHR39QsJBlKOnn7BIQoBLro-hgqOfi4Kzi6GxuYKnn4Kzv6-QMWOIZ7-fjwMrGmJOcWpvFCam0HBzTXE2UM3tSA_PrW4IDE5NS-1JN41wMTE0NjAxMDR0JgIJQCKrypE</recordid><startdate>20240814</startdate><enddate>20240814</enddate><creator>KUZMANOV, Ivan</creator><creator>PENCHEVA, Nora</creator><creator>BLUM, Jordan</creator><creator>FELLERMEIER-KOPF, Sina</creator><creator>SAHIN, Ugur</creator><creator>PAULMANN, Claudia</creator><creator>BREIJ, Esther C. W</creator><creator>BECKMANN, Karsten</creator><creator>MUIK, Alexander</creator><creator>LABRIJN, Aran</creator><creator>HIBBERT, Richard</creator><creator>GARRIDO CASTRO, Patricia</creator><creator>DE KREUK, Bart-Jan</creator><creator>GIESEKE, Friedericke</creator><creator>GUELEN, Lars</creator><creator>NÜRMBERGER, Kristina</creator><creator>JURE-KUNKEL, Maria,N</creator><creator>NEIJSSEN, Joost</creator><creator>SCHUURMAN, Janine</creator><scope>EVB</scope></search><sort><creationdate>20240814</creationdate><title>MULTISPECIFIC BINDING AGENTS AGAINST PD-L1 AND CD137 IN COMBINATION</title><author>KUZMANOV, Ivan ; PENCHEVA, Nora ; BLUM, Jordan ; FELLERMEIER-KOPF, Sina ; SAHIN, Ugur ; PAULMANN, Claudia ; BREIJ, Esther C. W ; BECKMANN, Karsten ; MUIK, Alexander ; LABRIJN, Aran ; HIBBERT, Richard ; GARRIDO CASTRO, Patricia ; DE KREUK, Bart-Jan ; GIESEKE, Friedericke ; GUELEN, Lars ; NÜRMBERGER, Kristina ; JURE-KUNKEL, Maria,N ; NEIJSSEN, Joost ; SCHUURMAN, Janine</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP4413040A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>2024</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>KUZMANOV, Ivan</creatorcontrib><creatorcontrib>PENCHEVA, Nora</creatorcontrib><creatorcontrib>BLUM, Jordan</creatorcontrib><creatorcontrib>FELLERMEIER-KOPF, Sina</creatorcontrib><creatorcontrib>SAHIN, Ugur</creatorcontrib><creatorcontrib>PAULMANN, Claudia</creatorcontrib><creatorcontrib>BREIJ, Esther C. W</creatorcontrib><creatorcontrib>BECKMANN, Karsten</creatorcontrib><creatorcontrib>MUIK, Alexander</creatorcontrib><creatorcontrib>LABRIJN, Aran</creatorcontrib><creatorcontrib>HIBBERT, Richard</creatorcontrib><creatorcontrib>GARRIDO CASTRO, Patricia</creatorcontrib><creatorcontrib>DE KREUK, Bart-Jan</creatorcontrib><creatorcontrib>GIESEKE, Friedericke</creatorcontrib><creatorcontrib>GUELEN, Lars</creatorcontrib><creatorcontrib>NÜRMBERGER, Kristina</creatorcontrib><creatorcontrib>JURE-KUNKEL, Maria,N</creatorcontrib><creatorcontrib>NEIJSSEN, Joost</creatorcontrib><creatorcontrib>SCHUURMAN, Janine</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>KUZMANOV, Ivan</au><au>PENCHEVA, Nora</au><au>BLUM, Jordan</au><au>FELLERMEIER-KOPF, Sina</au><au>SAHIN, Ugur</au><au>PAULMANN, Claudia</au><au>BREIJ, Esther C. W</au><au>BECKMANN, Karsten</au><au>MUIK, Alexander</au><au>LABRIJN, Aran</au><au>HIBBERT, Richard</au><au>GARRIDO CASTRO, Patricia</au><au>DE KREUK, Bart-Jan</au><au>GIESEKE, Friedericke</au><au>GUELEN, Lars</au><au>NÜRMBERGER, Kristina</au><au>JURE-KUNKEL, Maria,N</au><au>NEIJSSEN, Joost</au><au>SCHUURMAN, Janine</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>MULTISPECIFIC BINDING AGENTS AGAINST PD-L1 AND CD137 IN COMBINATION</title><date>2024-08-14</date><risdate>2024</risdate><abstract>The present invention provides combination therapy using a binding agent that binds to human CD137 and to human PD-L1 in combination with a PD-1 inhibitor to reduce or prevent progression of a tumor or treating cancer.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; fre ; ger |
| recordid | cdi_epo_espacenet_EP4413040A1 |
| source | esp@cenet |
| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | MULTISPECIFIC BINDING AGENTS AGAINST PD-L1 AND CD137 IN COMBINATION |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-15T03%3A24%3A18IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=KUZMANOV,%20Ivan&rft.date=2024-08-14&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EEP4413040A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |