PROCESS FOR PREPARING SARTAN ACTIVE COMPOUNDS HAVING A TETRAZOLE RING

PROCESS FOR PREPARING SARTAN ACTIVE COMPOUNDS HAVING A TETRAZOLE RING

The present disclosure relates to a process for manufacturing at least one sartan active compound of formula (I)wherein R is selected from a group of formulas (1), (2), (3), (4) and (5), comprising the tetrazolylation of one compound of formula (II)wherein R is as previously defined, in a reactional...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: CRUCIANI, Paul, GALIBOURG, Isabelle, GRIMAUD, Bernard
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The present disclosure relates to a process for manufacturing at least one sartan active compound of formula (I)wherein R is selected from a group of formulas (1), (2), (3), (4) and (5), comprising the tetrazolylation of one compound of formula (II)wherein R is as previously defined, in a reactional medium with at least one azide derivative, wherein benzylic azide impurities formed during said tetrazolylation are converted into aldehyde derivatives.