BENZODIAZEPINE DERIVATIVES AS GABA A GAMMA1 PAM
The invention provides novel heterocyclic compounds having the general formula (I), and pharmaceutically acceptable salts thereof, wherein R1 to R5 and X are as described herein.Further provided are pharmaceutical compositions including the compounds, processes of manufacturing the compounds and met...
Gespeichert in:
| Hauptverfasser: | , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; fre ; ger |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | RUNTZ-SCHMITT, Valerie HUMM, Roland HANLON, Steven Paul HERNANDEZ, Maria-Clemencia KOBLET, Andreas OLIVARES MORALES, Andrés Miguel GOBBI, Luca CECERE, Giuseppe |
| description | The invention provides novel heterocyclic compounds having the general formula (I), and pharmaceutically acceptable salts thereof, wherein R1 to R5 and X are as described herein.Further provided are pharmaceutical compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds as medicaments, in particular methods of using the compounds for the treatment or prevention of acute neurological disorders, chronic neurological disorders and/or cognitive disorders. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_EP4405043A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>EP4405043A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_EP4405043A13</originalsourceid><addsrcrecordid>eNrjZNB3cvWL8nfxdIxyDfD0c1VwcQ3yDHMM8QxzDVZwDFZwd3RyVHAEUr6-joYKAY6-PAysaYk5xam8UJqbQcHNNcTZQze1ID8-tbggMTk1L7Uk3jXAxMTA1MDE2NHQmAglAJYQJRU</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>BENZODIAZEPINE DERIVATIVES AS GABA A GAMMA1 PAM</title><source>esp@cenet</source><creator>RUNTZ-SCHMITT, Valerie ; HUMM, Roland ; HANLON, Steven Paul ; HERNANDEZ, Maria-Clemencia ; KOBLET, Andreas ; OLIVARES MORALES, Andrés Miguel ; GOBBI, Luca ; CECERE, Giuseppe</creator><creatorcontrib>RUNTZ-SCHMITT, Valerie ; HUMM, Roland ; HANLON, Steven Paul ; HERNANDEZ, Maria-Clemencia ; KOBLET, Andreas ; OLIVARES MORALES, Andrés Miguel ; GOBBI, Luca ; CECERE, Giuseppe</creatorcontrib><description>The invention provides novel heterocyclic compounds having the general formula (I), and pharmaceutically acceptable salts thereof, wherein R1 to R5 and X are as described herein.Further provided are pharmaceutical compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds as medicaments, in particular methods of using the compounds for the treatment or prevention of acute neurological disorders, chronic neurological disorders and/or cognitive disorders.</description><language>eng ; fre ; ger</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240731&DB=EPODOC&CC=EP&NR=4405043A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76292</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240731&DB=EPODOC&CC=EP&NR=4405043A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>RUNTZ-SCHMITT, Valerie</creatorcontrib><creatorcontrib>HUMM, Roland</creatorcontrib><creatorcontrib>HANLON, Steven Paul</creatorcontrib><creatorcontrib>HERNANDEZ, Maria-Clemencia</creatorcontrib><creatorcontrib>KOBLET, Andreas</creatorcontrib><creatorcontrib>OLIVARES MORALES, Andrés Miguel</creatorcontrib><creatorcontrib>GOBBI, Luca</creatorcontrib><creatorcontrib>CECERE, Giuseppe</creatorcontrib><title>BENZODIAZEPINE DERIVATIVES AS GABA A GAMMA1 PAM</title><description>The invention provides novel heterocyclic compounds having the general formula (I), and pharmaceutically acceptable salts thereof, wherein R1 to R5 and X are as described herein.Further provided are pharmaceutical compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds as medicaments, in particular methods of using the compounds for the treatment or prevention of acute neurological disorders, chronic neurological disorders and/or cognitive disorders.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNB3cvWL8nfxdIxyDfD0c1VwcQ3yDHMM8QxzDVZwDFZwd3RyVHAEUr6-joYKAY6-PAysaYk5xam8UJqbQcHNNcTZQze1ID8-tbggMTk1L7Uk3jXAxMTA1MDE2NHQmAglAJYQJRU</recordid><startdate>20240731</startdate><enddate>20240731</enddate><creator>RUNTZ-SCHMITT, Valerie</creator><creator>HUMM, Roland</creator><creator>HANLON, Steven Paul</creator><creator>HERNANDEZ, Maria-Clemencia</creator><creator>KOBLET, Andreas</creator><creator>OLIVARES MORALES, Andrés Miguel</creator><creator>GOBBI, Luca</creator><creator>CECERE, Giuseppe</creator><scope>EVB</scope></search><sort><creationdate>20240731</creationdate><title>BENZODIAZEPINE DERIVATIVES AS GABA A GAMMA1 PAM</title><author>RUNTZ-SCHMITT, Valerie ; HUMM, Roland ; HANLON, Steven Paul ; HERNANDEZ, Maria-Clemencia ; KOBLET, Andreas ; OLIVARES MORALES, Andrés Miguel ; GOBBI, Luca ; CECERE, Giuseppe</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP4405043A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>2024</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>RUNTZ-SCHMITT, Valerie</creatorcontrib><creatorcontrib>HUMM, Roland</creatorcontrib><creatorcontrib>HANLON, Steven Paul</creatorcontrib><creatorcontrib>HERNANDEZ, Maria-Clemencia</creatorcontrib><creatorcontrib>KOBLET, Andreas</creatorcontrib><creatorcontrib>OLIVARES MORALES, Andrés Miguel</creatorcontrib><creatorcontrib>GOBBI, Luca</creatorcontrib><creatorcontrib>CECERE, Giuseppe</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>RUNTZ-SCHMITT, Valerie</au><au>HUMM, Roland</au><au>HANLON, Steven Paul</au><au>HERNANDEZ, Maria-Clemencia</au><au>KOBLET, Andreas</au><au>OLIVARES MORALES, Andrés Miguel</au><au>GOBBI, Luca</au><au>CECERE, Giuseppe</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>BENZODIAZEPINE DERIVATIVES AS GABA A GAMMA1 PAM</title><date>2024-07-31</date><risdate>2024</risdate><abstract>The invention provides novel heterocyclic compounds having the general formula (I), and pharmaceutically acceptable salts thereof, wherein R1 to R5 and X are as described herein.Further provided are pharmaceutical compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds as medicaments, in particular methods of using the compounds for the treatment or prevention of acute neurological disorders, chronic neurological disorders and/or cognitive disorders.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; fre ; ger |
| recordid | cdi_epo_espacenet_EP4405043A1 |
| source | esp@cenet |
| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | BENZODIAZEPINE DERIVATIVES AS GABA A GAMMA1 PAM |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-27T08%3A48%3A39IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=RUNTZ-SCHMITT,%20Valerie&rft.date=2024-07-31&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EEP4405043A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |