TWO-LAYER SUPPORT FOR THE PREPARATION OF (EPI)DERMAL EQUIVALENT OR SKIN EQUIVALENT

The present invention relates to a method for producing a dermal or skin or epidermal equivalent on a two-layer substrate comprising a layer of at least 200 nm in thickness and having a porosity less than or equal to 5 μm formed by electrospinning of a composition comprising at least one polymer, an...

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Bibliographische Detailangaben
Hauptverfasser:	RIELLAND, Maïté, LYNCH, Barbara, GIRARD, Fabien, BOYERA, Nathalie
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES DISINFECTION, STERILISATION, OR DEODORISATION OF AIR HUMAN NECESSITIES HYGIENE MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL
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Beschreibung
Zusammenfassung:	The present invention relates to a method for producing a dermal or skin or epidermal equivalent on a two-layer substrate comprising a layer of at least 200 nm in thickness and having a porosity less than or equal to 5 μm formed by electrospinning of a composition comprising at least one polymer, and a layer of at least 20 μm in thickness and having a porosity greater than or equal to 20 μm formed by electrowriting of a composition comprising at least one polymer. The application also relates to the skin or dermal or epidermal equivalent that can be obtained with said method, the use of a dermal equivalent or a skin equivalent or an epidermal equivalent for screening compounds and finally the use thereof in wound dressing or for skin grafts.