FUSED HETEROCYCLIC RINGS AS RIPK1 INHIBITORS

FUSED HETEROCYCLIC RINGS AS RIPK1 INHIBITORS

The invention provides novel substituted heterocyclic rings represented by Formula I, or a pharmaceutically acceptable salt, solvate, polymorph, ester, tautomer or prodrug thereof, and a composition comprising these compounds. The compounds provided can be used as inhibitors of RIPK1 and the therape...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: PARK, Kitae, KIM, Minha, SEO, Jeongbeob, HAN, Cheolkyu, CHOI, Sungmin, KIM, Jinyoung, JEON, Seeun, KWON, Youngeun, KANG, Hongjun, JEONG, Heejin, YOON, Cheolhwan, KIM, Sunjoo, KIM, Namhee, HAN, Sangbae, MIN, Jiae, YANG, Inho
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The invention provides novel substituted heterocyclic rings represented by Formula I, or a pharmaceutically acceptable salt, solvate, polymorph, ester, tautomer or prodrug thereof, and a composition comprising these compounds. The compounds provided can be used as inhibitors of RIPK1 and the therapeutic methods.