NON-INVASIVE ASSESSMENT OF GLYMPHATIC FLOW AND NEURODEGENERATION FROM A WEARABLE DEVICE

A computer-implemented method and system includes accessing neurophysiological and neurovascular data recorded during sleep. A function mapping is executed from said neurophysiological and neurovascular data to a target that is one of a glymphatic flow marker, a molecular analysis marker of neurodeg...

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Hauptverfasser: STUDENT, Joerg C, KAPLAN, Jonathan I, DAGUM, Paul, GIOVANGRANDI, Laurent B, WHIPPLE, Nathan, WEBER, Carl J, KOVACS, Gregory T. A
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:A computer-implemented method and system includes accessing neurophysiological and neurovascular data recorded during sleep. A function mapping is executed from said neurophysiological and neurovascular data to a target that is one of a glymphatic flow marker, a molecular analysis marker of neurodegeneration, or a neuroimaging marker of neurodegeneration. A target prediction model is output based on the function mapping. The target prediction model can receive new neurophysiological and neurovascular data and output a predicted marker of neurodegeneration.