DELIVERY OF LOW SURFACE TENSION COMPOSITIONS TO THE PULMONARY SYSTEM VIA ELECTRONIC BREATH ACTUATED DROPLET DELIVERY DEVICE

A droplet delivery device and related methods for delivering a low surface tension composition as a stream of droplets to a subject for pulmonary use is disclosed. The droplet delivery device includes a housing, a reservoir, an ejector mechanism, and at least one differential pressure sensor. The dr...

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Bibliographische Detailangaben
Hauptverfasser: HUNTER, Charles Eric, HEBRANK, John H, THOMAS, Brian H, CLEMENTS, Judson Sidney
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:A droplet delivery device and related methods for delivering a low surface tension composition as a stream of droplets to a subject for pulmonary use is disclosed. The droplet delivery device includes a housing, a reservoir, an ejector mechanism, and at least one differential pressure sensor. The droplet delivery device is automatically breath actuated by the user when the differential pressure sensor senses a predetermined pressure change within housing. The ejector mechanism includes a piezoelectric actuator and an aperture plate, the aperture plate having a plurality of openings formed through its thickness, and one or more surfaces configured to provide a desired surface contact angle, and the piezoelectric actuator operable to oscillate the aperture plate at a frequency to thereby generate the ejected stream of droplets.