COMPOSITIONS AND METHODS FOR MODULATING NLRP3 OR NLRP1 EXPRESSION

Described herein are compositions of an antisense oligonucleotide capable of binding to NACHT, LRR and PYD domains-containing protein 3 (NLRP3) or NLRP1 mRNA for modulating gene expressions. Also described herein are methods for using the compositions described herein for modulating gene expressions...

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Bibliographische Detailangaben
Hauptverfasser:	JIN, Bohan, CHEN, Lishan, WONG, Timothy Preston
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Described herein are compositions of an antisense oligonucleotide capable of binding to NACHT, LRR and PYD domains-containing protein 3 (NLRP3) or NLRP1 mRNA for modulating gene expressions. Also described herein are methods for using the compositions described herein for modulating gene expressions or for treating inflammasome-associate disease.