INDOLE COMPOUNDS AND USES THEREOF IN THE TREATEMENT OF CYSTIC FIBROSIS

The invention relates to heterocyclic compounds, pharmaceutically acceptable salts thereof, and pharmaceutical preparations thereof. Also described herein are compositions and the use of such compounds in methods of treating diseases and conditions mediated by deficient CFTR activity, in particular...

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Hauptverfasser: BORCHERDING, David, NIEDUZAK, Thaddeus, VAZ, Roy, LI, Yi, GAO, Zhongli, LIAO, Junkai, HURLBUT, Gregory, BARRAGUE, Matthieu, METZ, Markus, GROSS, Alexandre, GOOD, Andrew, HIRTH, Bradford, GILLESPY, Timothy, Alan, THURAIRATNAM, Sukanthini, RUVINSKY, Anatoly, LIU, Jinyu, MUNSON, Mark, KOTHE, Michael
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The invention relates to heterocyclic compounds, pharmaceutically acceptable salts thereof, and pharmaceutical preparations thereof. Also described herein are compositions and the use of such compounds in methods of treating diseases and conditions mediated by deficient CFTR activity, in particular cystic fibrosis.