METHOD FOR PRODUCING 2?-MODIFIED GUANOSINE COMPOUND

To provide a novel method for producing a 2'-modified guanosine compound of the following formula.In the formula, R1 and R2 are the same as or different from each other and are hydrogen atoms, substitutable C1-6 alkyl groups, substitutable C7-16 aralkyl groups, substitutable C2-6 alkenyl groups...

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Bibliographische Detailangaben
Hauptverfasser:	UMEDA, Yasuhiro, MATSUOKA, Seiya, MIMORI, Yuji, MORODOME, Keisuke
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY DERIVATIVES THEREOF HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SUGARS
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Beschreibung
Zusammenfassung:	To provide a novel method for producing a 2'-modified guanosine compound of the following formula.In the formula, R1 and R2 are the same as or different from each other and are hydrogen atoms, substitutable C1-6 alkyl groups, substitutable C7-16 aralkyl groups, substitutable C2-6 alkenyl groups, substitutable C2-6 alkynyl groups or substitutable C6-14 aryl groups, n is 0 or 1, when n is 1, P1 is a protecting group bonded to a nitrogen atom through a single bond, and when n is 0, P1 is a protecting group bonded to a nitrogen atom through a double bond.