HYDANTOIN COMPOUND AND MEDICAL USE THEREOF

Provided are a hydantoin compound as represented by formula (I) or a pharmaceutically acceptable salt thereof and the medical use thereof. The compound has a strong agonistic action on PPARα and PPARδ, has a good selectivity to PPARγ, and has good pharmacokinetic properties. The compound or a pharma...

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Bibliographische Detailangaben
Hauptverfasser:	SUN, Hongbin, XIANG, Jiehao, WANG, Yanyan, LIU, Hui, FENG, Zhiqi, DAI, Liang, YUN, Yinling, LIU, Xin, YUAN, Haoliang, XU, Xiangrui, SUN, Gang
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Provided are a hydantoin compound as represented by formula (I) or a pharmaceutically acceptable salt thereof and the medical use thereof. The compound has a strong agonistic action on PPARα and PPARδ, has a good selectivity to PPARγ, and has good pharmacokinetic properties. The compound or a pharmaceutically acceptable salt, prodrug, deuterated compound or solvate thereof can be used for preparing a PPARα/δ dual agonist, and is used for preparing a drug for preventing or treating diseases mediated by PPARα and/or PPARδ.