DEHYDROGENASE MUTANTS AND APPLICATIONS THEREOF IN AMINO ACID SYNTHESIS

The present invention relates to a modified dehydrogenase, wherein one or more amino acid residues of the dehydrogenase are modified as compared to an unmodified dehydrogenase, and wherein the modified dehydrogenase has an increased ratio of leucine dehydrogenase or isoleucine dehydrogenase activity...

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Bibliographische Detailangaben
Hauptverfasser:	DUMON-SEIGNOVERT, Laurence, RAYNAUD, Céline, DESFOUGERES, Thomas, VASSEUR, Perrine, BOUDON, Jean-Baptiste
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to a modified dehydrogenase, wherein one or more amino acid residues of the dehydrogenase are modified as compared to an unmodified dehydrogenase, and wherein the modified dehydrogenase has an increased ratio of leucine dehydrogenase or isoleucine dehydrogenase activity to valine dehydrogenase activity as compared to the unmodified dehydrogenase, and applications thereof.