INHIBITORS OF NLRP3

The present invention relates to novel compounds of Formulae I-XI: wherein each A, A′, Q, Q′, W, Rw, Y, and Z, and -- are as defined herein, which inhibit NOD-like receptor protein 3 (NLRP3) inflammasome activity. The invention further relates to the processes for their preparation, pharmaceutical c...

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Hauptverfasser:	BEJCEK, Lauren, HOSSEYNI, Seyedmorteza, SYDORENKO, Nadiya, PILLAI, Meenu, HUARTE, Eduardo, ZHANG, Nanjing, GONG, Hua, Handoko, LI, Jing, BARRAZA, Scott, J, WOLL, Matthew, G, ALAM, Rauful, PARKER, Erica, N, ZHANG, Xiaoyan, GILBERT, Bradley, B, NIEDERER, Kyle, ZHENG, Tianyi, TURPOFF, Anthony, JEON, Woohyung, LIU, Yao, ZHANG, Yan, RASTELLI, Ettore
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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