USE OF CCR3-INHIBITORS

USE OF CCR3-INHIBITORS

The present invention relates to CCR3 inhibitors of formula 1,whereinR1is H, C1-6-alkyl, C0-4-alkyl-C3-6-cycloalkyl, C1-6-haloalkyl;R2is H, C1-6-alkyl;Xis an anion selected from the group consisting of chloride or ½ dibenzoyltartratejis 1 or 2.for use as a medicament for the treatment of diseases se...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: BOUYSSOU, Thierry, NIVENS, Michael Chadham, GOEGGEL, Rolf, SEITHER, Peter
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The present invention relates to CCR3 inhibitors of formula 1,whereinR1is H, C1-6-alkyl, C0-4-alkyl-C3-6-cycloalkyl, C1-6-haloalkyl;R2is H, C1-6-alkyl;Xis an anion selected from the group consisting of chloride or ½ dibenzoyltartratejis 1 or 2.for use as a medicament for the treatment of diseases selected from dry age-related macular degeneration (dAMD), wet age-related macular degeneration (wAMD), retinopathy of prematurity (ROP), central retinal vein occlusion (CRVO), nasal polyposis, eosinophilic esophagitis, eosinophillic gastroenteritis (e.g. eosinophilic gastritis and eosinophilic ententeritis), hypereosinophilic syndrome and Churg Strauss syndrome.