DISCRIMINATION OF ANTIBIOTIC RESISTANT AND SENSITIVE SAMPLES

A method of determining antibiotic resistance of bacteria includes dividing a sample including the bacteria into a plurality of sub-samples, mixing labeling: agents with each of the plurality of sub-samples. Each of the labeling agents is detectible via a detection system including a sensor to detec...

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Bibliographische Detailangaben
Hauptverfasser: HEMPEL, John D, KELLUM, Jr., John Alston, EDGAR, Robert Hugh, WHITE, Cierra Lynn, VIATOR, John, Andrew
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:A method of determining antibiotic resistance of bacteria includes dividing a sample including the bacteria into a plurality of sub-samples, mixing labeling: agents with each of the plurality of sub-samples. Each of the labeling agents is detectible via a detection system including a sensor to detect photoacoustic waves. The labeling: agents are further active to selectively bind with the bacteria. The method further includes applying an antibiotic to one or more of the plurality of sub-samples and not to one or more others of the plurality of sub- samples, characterizing at least one of the sub- samples to which the antibiotic has been applied and at least one of the sub-samples to which no antibiotic has been applied after a determined period of time via the detection system, and determining antibiotic resistance of the bacteria on the basis of the characterization via the detection system.