PHARMACEUTICAL COMPOSITION IN THE FORM OF VEGETABLE OIL-BASED NANOEMULSION, MULTIPHASE COMPOSITION AND METHOD OF PREPARATION OF THESE COMPOSITIONS

The first object of the invention is a nanoemulsion composition based on vegetable oil, characterized in that it comprises vegetable oil, which is rapeseed oil, in an amount of 10 to 60 parts by mass of rapeseed oil, 12 to 20 parts by mass of P188 block copolymer of ethylene oxide and oxide propylene, from 40 to 60 parts by mass of purified water, from 1 to 12 parts by mass of sorbitan monooleate, from 5 to 20 parts by mass of polyol, from 0.10 to 0.50 parts by mass of lactic acid, from 0.5 to 5.0 parts by mass of clotrimazole, wherein the oil phase droplets have a hydrodynamic diameter ranging from 50 nm to 70 nm. The second object of the invention is a multiphase composition based on nanoemulsion of vegetable oil, characterized in that it contains a polysaccharide phase in an amount from 10 to 50 parts by mass and a nanoemulsion according to the first object of the invention in an amount from 50 to 90 parts by mass, wherein the multiphase composition is in the form of a nanoemulgel wherein the multiphase composition has a dynamic viscosity from 220 mPa * s to 580 mPa * s.