PROCESSES FOR THE PREPARATION OF (S)-2-(4-CHLORO-2-METHOXYPHENYL)-2-((3-METHOXY-5-(METHYLSULFONYL)PHENYL)AMINO)-1 -(1H-INDOL-3-YL)ETHENONE DERIVATIVES

PROCESSES FOR THE PREPARATION OF (S)-2-(4-CHLORO-2-METHOXYPHENYL)-2-((3-METHOXY-5-(METHYLSULFONYL)PHENYL)AMINO)-1 -(1H-INDOL-3-YL)ETHENONE DERIVATIVES

The present invention relates to novel chiral synthesis of mono- or di-substituted indole compounds of formula (I)wherein:R1 is H, R2 is F and R3 is H or CH3,R1 is H, CH3 or F, R2 is OCH3 and R3 is H andR1 is H, R2 is OCH3 and R3 is CH3,R1 is CH3, R2 is F and R3 is H,R1 is CF3 or OCF3, R2 is H and R...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: COESEMANS, Erwin, SCHWEITZERAPUT, Bertrand, WU, Kai, ERIKSSON, Carl Arne Magnus, OOST, Rik
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The present invention relates to novel chiral synthesis of mono- or di-substituted indole compounds of formula (I)wherein:R1 is H, R2 is F and R3 is H or CH3,R1 is H, CH3 or F, R2 is OCH3 and R3 is H andR1 is H, R2 is OCH3 and R3 is CH3,R1 is CH3, R2 is F and R3 is H,R1 is CF3 or OCF3, R2 is H and R3 is H,R1 is OCF3, R2 is OCH3 and R3 is H andR1 is OCF3, R2 is H and R3 is CH3.