MECHANISMS FOR BRAIN ANALYSIS

A method for localizing structural connectivity biomarkers in neurological diseases, includes dividing a diffusion magnetic resonance imaging brain volume into a set of connected brain regions; extracting three-dimensional voxels along fiber connections which structurally connect the connected brain...

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1. Verfasser: Schwab, Evan
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:A method for localizing structural connectivity biomarkers in neurological diseases, includes dividing a diffusion magnetic resonance imaging brain volume into a set of connected brain regions; extracting three-dimensional voxels along fiber connections which structurally connect the connected brain regions, wherein the brain regions comprise bundles of neurons; applying a deep neural network to diffusion magnetic resonance imaging features extracted from the three-dimensional voxels for each set of fiber connections which structurally connect brain regions; outputting a disease classification based on applying the deep neural network; and applying multi-instance learning to predict whether each fiber connection is indicative of a healthy brain or a diseased brain.