RECEPTOR-INTERACTING PROTEIN INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF

Provided are a compound as a receptor-interacting protein (RIP) inhibitor, a preparation method therefor, and a use thereof, relating to the field of chemical medicines. The compound is a compound as represented by formula (I), or a salt thereof, or a stereoisomer thereof, or a solvate thereof, or a...

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Hauptverfasser: ZHAN, Wei, QIN, Chuanjun, LAI, Yongxin, ZENG, Yisheng, HU, Xiaojun, XIE, Jian, DONG, Renghan, YANG, Tai, PENG, Jian, PENG, Xiangyang, GUANG, Bing, LIU, Jin, XU, Qing, HUANG, Sheng
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Provided are a compound as a receptor-interacting protein (RIP) inhibitor, a preparation method therefor, and a use thereof, relating to the field of chemical medicines. The compound is a compound as represented by formula (I), or a salt thereof, or a stereoisomer thereof, or a solvate thereof, or a prodrug thereof. The compound has good inhibitory activity on humanized RIP1 kinase, and can be used for preparing drugs for resisting inflammation, resisting tumors and the like.