PHARMACEUTICAL COMPOSITIONS OF AN EPIDERMAL GROWTH FACTOR RECEPTOR INHIBITOR

PHARMACEUTICAL COMPOSITIONS OF AN EPIDERMAL GROWTH FACTOR RECEPTOR INHIBITOR

The present disclosure relates to pharmaceutical compositions comprising an intragranular phase, wherein the intragranular phase comprises: (i) an amorphous solid dispersion comprising Compound (I) or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable polymer, and (ii) a s...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: KINKEMA, Caitlin, N, VAZE, Onkar, Shripad, MEDENDORP, Clare, Aubrey, MAZAIK, Debra, L
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The present disclosure relates to pharmaceutical compositions comprising an intragranular phase, wherein the intragranular phase comprises: (i) an amorphous solid dispersion comprising Compound (I) or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable polymer, and (ii) a surfactant; and an extragranular phase, wherein the extragranular phase comprises a surfactant. The present disclosure also relates to methods of using said compositions in the treatment of various disorders.